PURE STEM VS ASCE+

New comparative studies on Adipose vs. Umbilical exosomes published in March 2026 explicitly outline the distinct clinical profiles of these powerful regenerative sources.

ASCE+ (Adipose-Derived): The data confirms that adipose exosomes are excellent for hydration and general extracellular matrix (ECM) remodeling because they are rich in VEGF (Vascular Endothelial Growth Factor).

🏆 Pure Stem (Umbilical-Derived): The new 2026 studies prove that Umbilical exosomes carry a significantly higher payload of TGF-beta and PDGF-BB. In clinical terms, this means Pure Stem delivers superior anti-inflammatory, photo-protective, and deep-tissue regenerative effects compared to adipose sources. It also yields up to 14x more anti-aging growth factors.

2. Concentration Density (The Math Still Wins)

ASCE+ (SRLV): Still sits at 5 Billion exosomes. It comes as 20mg of powder mixed with a 5ml liquid diluent, resulting in a density of 1 Billion exosomes per ml.

🏆 Pure Stem: Delivers 7.58 Billion exosomes with over 99% purity. Because it’s contained within a much smaller 0.5ml volume upon reconstitution, the density is over 15 Billion exosomes per ml.

At HaruSkin, we are offering clients a highly concentrated “shot” of regenerative power compared to a diluted ASCE+ mixture.

3. Stability and Logistics Both products are lyophilized (freeze-dried), which is an incredible advantage for securing clinical-grade skincare online. It ensures the biological integrity of the exosomes is perfectly preserved during shipping across the world from Japan without degrading, guaranteeing maximum potency from the moment it arrives at your door.